My guest is Dr. Kyle Gillett, MD, a dual board-certified physician in family medicine and obesity medicine and an expert in optimizing hormone levels to improve overall health and well-being in both men and women. We discuss how to improve hormones using behavioral, nutritional, and exercise-based tools and safely and rationally approach supplementation and hormone therapies. We discuss testosterone and estrogen and how those hormones relate to fertility, mood, aging, relationships, disease pathologies, thyroid hormone, growth hormone, prolactin, dopamine and peptides that impact physical and mental health and vitality across the lifespan. The episode is rich with scientific mechanisms and tools for people to consider.
#HubermanLab #Testosterone #Estrogen
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Timestamps
00:00:00 Dr. Kyle Gillett, MD, Hormone Optimization
00:03:10 The Brain-Body Contract
00:04:10 Thesis, InsideTracker, ROKA
00:08:24 Preventative Medicine & Hormone Health
00:14:17 The Six Pillars of Hormone Health Optimization
00:17:14 Diet for Hormone Health, Blood Testing
00:20:21 Exercise for Hormone Health
00:21:06 Caloric Restriction, Obesity & Testosterone
00:23:55 Intermittent Fasting, Growth Hormone (GH), IGF-1
00:29:08 Sleep Quality & Hormones
00:35:03 Testosterone in Women
00:38:55 Dihydrotestosterone (DHT), Hair Loss
00:43:46 DHT in Men and Women, Turmeric/Curcumin, Creatine
00:50:10 5-Alpha Reductase, Finasteride, Saw Palmetto
00:52:30 Hair loss, DHT, Creatine Monohydrate
00:55:07 Hair Regrowth, Male Pattern Baldness
00:58:12 Polycystic Ovary Syndrome (PCOS), Inositol, DIM
01:04:00 Oral Contraception, Perceived Attractiveness, Fertility
01:10:31 Testosterone & Marijuana or Alcohol
01:14:27 Sleep Supplement Frequency
01:15:34 Testosterone Supplementation & Prostate Cancer
01:20:24 Prostate Health, Dietary Fiber, Saw Palmetto, C-Reactive Protein
01:24:05 Prostate Health & Pelvic Floor, Viagra, Tadalafil
01:30:54 Testosterone Replacement Therapy (TRT)
01:35:17 Estrogen & Aromatase Inhibitors, Calcium D-Glucarate, DIM
01:39:28 Lifestyle Factors to Increase Testosterone/Estrogen Levels, Dietary Fats
01:45:34 Aromatase Supplements: Ecdysterone, Turkesterone
01:47:04 Tongkat Ali (Long Jack), Estrogen/Testosterone levels
01:52:25 Fadogia Agrestis, Luteinizing Hormone (LH), Frequency
01:56:44 Boron, Sex Hormone Binding Globulin (SHBG)
01:58:13 Human Chorionic Gonadotropin (hCG), Fertility
02:04:18 Prolactin & Dopamine, Pituitary Damage
02:08:34 Augmenting Dopamine Levels: Casein, Gluten, Vitamin E, Vitamin B6 (P5P)
02:12:30 L-Carnitine & Fertility, TMAO & Allicin (Garlic)
02:18:19 Blood Test Frequency
02:19:41 Long-Term Relationships & Effects on Hormones
02:25:33 Nesting Instincts: Prolactin, Childbirth & Relationships
02:29:05 Cold & Hot Exposure, Hormones & Fertility
02:32:34 Peptide Hormones: Insulin, Tesamorelin, Ghrelin
02:37:24 Growth Hormone-Releasing Peptides (GHRPs)
02:39:38 BPC-157 & Injury, Dosing Frequency
02:45:23 Uses for Melanotan
02:48:21 Spiritual Health Impact on Mental & Physical Health
02:54:18 Caffeine & Hormones
02:56:19 Neural Network Newsletter, Zero-Cost Support, YouTube Feedback, Spotify Review, Apple Reviews, Sponsors, Patreon, Thorne, Instagram, Twitter, Brain-Body Contract
Disclaimer: https://hubermanlab.com/disclaimer
Title Card Photo Credit: Mike Blabac – https://www.blabacphoto.com
Audio Engineering: Joel Hatstat at High Jump Media
