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Teacher Shane Crotty, PhD joins MedCram to answer a series of COVID vaccine concerns including what are the possibilities of long-lasting side results? How safe is RNA vaccine (i.e. Pfizer/ BioNTech and Moderna Vaccines) technology? How long does mRNA from a vaccine stay in our cells?
Shane Crotty, PhD is a Professor at the La Jolla Institute for Immunology, Center for Infectious Disease and Vaccine Research, Crotty Lab. Professor Crotty also has an academic appointment with the University of California San Diego. See his full bio here: https://www.lji.org/labs/crotty/#overview.
Professor Crotty on Twitter: https://twitter.com/profshanecrotty.
Recruiter: Kyle Allred, Physician Assistant, Producer and Co-Founder of MedCram.com.
See our brand-new interview with Prof. Crotty on how virus mutations (UK version and S. African variation) might be affecting COVID-19 transmission and vaccine efficacy.
Research referenced in this video from Prof. Crotty and his team was published Jan. 6, 2021, in the distinguished Journal Science: https://science.sciencemag.org/content/early/2021/01/05/science.abf4063.full.
New york city Times post highlighting Prof. Shane Crotty’s research study: https://www.nytimes.com/2020/11/17/health/coronavirus-immunity.html.
00:00 Introducing Prof. Shane Crotty’s Research.
0:35 How long does COVID-19 “immune memory” last?
0:57 The three primary aspects of immune memory: antibodies, killer T cells, and helper T cells.
2:25 The anatomy (protein makeup) of SARS-CoV-2.
3:02 Why is spike protein the main target?
5:17 Could a mutation permit SARS-CoV-2 to infect without spike protein?
7:02 Utilizing lipid nanoparticles to deliver mRNA and the role of RNA generally.
9:52 What human cells does an RNA vaccine go into?
10:36 How long does mRNA from a vaccine remain in human cells?
11:44 What else enters vaccines besides mRNA and lipid nanoparticles? Any adjuvants or preservatives?
12:30 Why are adjuvants used in numerous vaccines?
14:08 Protein production from mRNA.
15:00 Why utilize the “extra” step of mRNA to code for protein antigens?
17:28 Are mRNA vaccines the future of vaccine advancement?
19:18 Any chance for mRNA to enter our cells’ nucleus?
20:55 The immune reaction to a coronavirus vaccine.
23:17 Expected signs from immune reaction to a vaccine vs. vaccine negative effects.
25:50 Should people who’ve had COVID-19 get immunized?
27:27 Immunity from COVID vaccine vs. a natural infection.
28:30 Why does the Pfizer vaccine requirement to be stored so cold?
29:04 What would you state to a member of the family who fidgets about a hurried vaccine and RNA innovation?
32:37 What about the possibility of long term side effects from RNA vaccines?
33:30 What’s next for Shane Crotty’s research study team?
( This video was taped on December 16, 2020).
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Teacher Shane Crotty, PhD joins MedCram to answer a series of COVID vaccine concerns including what are the opportunities of long-lasting side effects? How safe is RNA vaccine (i.e. Pfizer/ BioNTech and Moderna Vaccines) innovation? How long does mRNA from a vaccine stay in our cells? Why does Pfizer’s vaccine need to stay SO cold?
Shane Crotty, PhD is a Professor at the La Jolla Institute for Immunology, Center for Infectious Disease and Vaccine Research, Crotty Lab.
